Maldi Spotting System

Analysis of complex peptide and/or protein samples in proteomics Coupling NanoLC to Maldi mass spectrometry provides an extremely powerful tool for the analysis of complex peptide and/or protein samples in proteomics. The Ekspot spotter/fraction collector deposits fractions eluted from the NanoLC onto a MALDI plate, while a built-in pump automatically adds the matrix.  High positioning accuracy ensures consistent spotting with maximum resolution. By eliminating flow splitting, Eksigent's proprietary microfluidic technology improves reproducibility and sensitivity and eliminates solvent waste.  The NanoLC's precise microscale flow control runs HPLC gradients at rates as low as 20 nL per minute.

Automation for LC / GC and LC-MS Syringe only technology The syringe only concept of the HTC PAL combines the manual sample injection procedure with the precision and throughput of a robotic liquid handling system. Samples are aspirated with a conventional syringe and are transferred directly into the sample loop. No error prone teflon tubing or transfer lines are involved during the sample loading process. Advanced performance The HTC PAL provides outstanding performance and maximum flexibility for your LC sample processing system. Sample capacity of > 600 2ml standard vials or up to 24 microplates within 50cm of benchspace are unmatched in the industry. Temperature controlled sample storage makes it easy to cool down samples to prevent degradation or to heat samples for kinetic studies. Using the optional 4 port or 10 port injection valve enables complex column switching procedures or internal loop configurations. Intelligent system control Choose between 3 options to control your HTC PAL instrument. The local handheld controller provides easy-to-learn, easy-to-use operation. For individual application requirements the PC based Windows 2000/XP control software Cycle Composer is available. For single keyboard operation of a whole LCMS system, various third party HTC PAL drivers are available. Chromatography Accessories and Supplies Tubing and Capillaries All of Applied Research tubing is extruded from virgin materials manufactured by the original manufacturer of each material. We do not allow substitutes for our raw materials. Fittings Applied Research SS fittings are manufactured different materials for both high and low pressure applications. We take a pride in our work and make sure that we only use the finest materials available. Filters and Frits All of Applied Research metal filters are manufactured by Applied Porous Technologies. All other material is manufactured in our own facilities. HPLC Columns Choose between Applied Research PEEK or SS column line in many different dimensions. Tools When working in Chromatography you will need a kaleidoscope of tools. Applied Research offers you all the tools you are looking for. Accessories Beside Solvent Recycler, Degasser and other useful accessories, Applied Research Europe offers a line of manual injection and switching valves

Rapid, high rapid  throughput analytical HPLC

Life Science (metabolomics), Pharmaceutical (drug development & discovery)  Why use ultra-high pressure when you can use the ExpressLC-100 and consume less solvent, save money, cut analysis time in half and realize high resolution and sensitivity? Read about the results GSK achieved using the ExpressLC-100 for open-access LC/MS. Use of the ExpressLC System for Peptide Separations Acid-Induced Degradation of Steroids in Rat Chow Use of the ExpressLC System for Chiral Drug Analysis Accelerated Thermal Degradation of Indomethacin High-speed Determination and Examination of High Molecular Weight Proteins with the ExpressLC System  Use of the ExpressLC System for Bioanalytical/ Pharmacokinetic Studies Use of the Eksigent ExpressLC System to Measure Chromatographic Hydrophobicity Index

NanoLC 2D

Proteomics,  Metabolomics, Biomarker discovery, phosphopeptide analysis                                                                                                                                                                    The NanoLC Proteomics system performs high-resolution separations of peptides before analysis by a mass spectrometer. The NanoLC system’s microscale flow control runs precise HPLC gradients at flow rates as low as 20 nL/min. Low flow rates provide maximum mass spectrometer sensitivity and contribute to the system’s ability to improve identification of low-abundance proteins.

Alexys 110

Analysis of catecholamines, serotonin, metanephrines, VMA, HVA and 5-HIAA in urine and/or plasma.                            The Alexys 110 has been developed for routine analysis in clinical, environmental and pharmaceutical laboratories. The system comprises a Decade II SDC, autosampler, pump, organiser, bottle rack and data acquisition software. The organiser has integrated degassing, pulse damper and mains power distributor for all the devices. The Decade II SDC has the same performance as the Decade II with advanced digital filtering and control for a single flow cell in DC mode. Complete kits are available consisting of column, mobile phase, sample prep, standards and calibrators. Key Features Fully controlled standardised system for routine analysis Built in solvent degassing and pulse control Ability to analyse vials and well plates with cooling Advanced digital filtering Complete kits for the analysis of catecholamines, serotonin, metanephrines, VMA, HVA and 5-HIAA in urine and/or plasm

Recipe ClinRep® HPLC Complete Kits - Diagnostics / Therapeutic Monitoring

Reference Materials, HPLC Complete Kits and HPLC Instruments for Medical Diagnostics. § Catecholamines in urine § Catecholamines in plasma § Serotonin in urine § Serotonin in plasma § Metanephrines in Urine § VMA, HVA, 5-HIAA in Urine

Product areas within our core competency include:                                                     Centrifugation Equipment Precision Liquid Handling Instruments Constant Temperature Incubators Orbital Shaking, Rocking, and Mixing Equipment Plastic Supplies Laboratory equipment and supplies to the bioscience and bioresearch market.

HTC PAL                             HTS PAL

High Throughput Screening , Combinatorial Chemistry, Flow Injection Analysis, Pharmaco-kinetic studies, DMPK,   ADMET                                                                                                Interfaces with any major LC-MS system.  Fast injection cycle time. Temperature controlled sample storage. Front End Automation for LC and LC-MS microplate applications. Up to 24 microplates within 50/80 cm bench space.

PRIM 500

Learning spectrophotometry techniques in biologi and biochemistry schools, running routine tests in clinical, veterinary, food analysis laboratories... Example of analysis methods Substrates: Albumine, Alcool, Ammonia, Bilirubin, Calcium, Chloride, Cholesterol, HDL/LDLcholesterol, CO2, Creatinine, Iron, Magnesium, RBC magnesium, Phospho-lipids, Phosphorus, Total protein, Triglycerides, Urea, Uric Acid... Enzyme: Acid/Alkalin, Phosphatase, Amylase, APO-Al, ASAT/GOT, ASAT/GTP, CK, CGT, LDH, Lipase, Nukleotidase...

Pastel UV

COD, BOD, TOC, TSS, NO3, SUR *Multiparametric measure : Organic matter (COD, BOD,TOC,TSS) specific compounds (NO3, Detergents) *All type of waters (Natural water, raw sewage water, treated water,process water) *Fast, reading in less than 1 minute *Convenient, easy-to-use *Without reagent *User friendly Gross weight : 9Kg Dimensions : 40 x 40 x 40

The ActiPix™ D100 UV Imaging Detector

Lab-on-capillary, Biocatalysis - monitoring nanoscale  biotransformations, Protein digests, Molecular size measurement, e.g. in biopharmaceuticals, Bioprocessing, Indirect detection, Lab-on-a-chip The Paraytec ActiPix™ D100 is a miniature capillary UV detector, designed for on-line monitoring at a single UV wavelength, particularly for use with the separation methods of liquid chromatography and capillary electrophoresis.